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Updated: Jul 7, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Early intralipid therapy may have prevented bupivacaine-associated cardiac arrest
Thomas McCutchen1, J C Gerancher
1Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA. mccutcq@netscape.net
Objective:
Local anesthetic-induced cardiotoxicity remains a complication of regional anesthesia, with the potential to result in cardiac arrest refractory to resuscitation. Successful resuscitation using Intralipid (Baxter Pharmaceuticals by Fresenius Kabi, Uppsala, Sweden), has been reported in 2 patients with bupivacaine-induced cardiac arrest.
Case Report:
We report another case for which Intralipid was used as part of a successful resuscitation in a patient with local anesthetic-induced cardiotoxicity.
Conclusions:
Early treatment with Intralipid may help prevent cardiac arrest and speed successful resuscitation efforts.
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