Prosthetic vascular graft infection: a multi-center review of surgical management

Eleonore Zetrenne1, Bryan C McIntosh, Mark H McRae

  • 1Aesthetic and Plastic Surgery Institute, University of California, Irvine, Orange, California.

Insights

Managing infected prosthetic vascular grafts remains challenging. This study reviews outcomes, emphasizing bacteriology and infection grade for better graft preservation and limb salvage strategies.

Area of Science:

  • Vascular Surgery
  • Infectious Diseases
  • Medical Device Management

Background:

  • Management of infected prosthetic vascular grafts is controversial.
  • Increasingly virulent bacterial strains and changing patient demographics complicate treatment.
  • Current management lacks a uniform standard despite advancements.

Purpose of the Study:

  • To review surgical management of major extracavitary prosthetic vascular graft infections.
  • To correlate outcomes with bacteriology and infection grade.
  • To inform improved graft preservation and limb salvage strategies.

Main Methods:

  • Multi-center retrospective review.
  • Analysis of outcomes based on bacteriology and infection severity (grade).
  • Evaluation of graft preservation and limb salvage rates.

Main Results:

  • Outcomes are influenced by bacteriology and infection grade.
  • Severity of infection impacts graft salvage success.
  • Bacteriology and grade are crucial for selecting graft salvage criteria.

Conclusions:

  • Bacteriology and infection severity must guide prosthetic vascular graft management.
  • A standardized approach is needed for infected prosthetic vascular grafts.
  • Improved strategies can enhance graft preservation and limb salvage rates.

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