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Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

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An Assay to Detect Protection of the Retinal Vasculature from Diabetes-Related Death in Mice
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Retinopathy and mortality. The Beijing Eye Study.

Liang Xu1, Ya Xing Wang, Xi Wei Xie

  • 1Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, 17 Hougou Street, Chong Wen Men, 100005 Beijing, China. xuliang5918@yahoo.com.cn

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|February 27, 2008
PubMed
Summary

Retinopathy, as defined by Early Treatment of Diabetic Retinopathy Study (ETDRS) criteria, is a significant risk factor for increased mortality in adult Chinese. This finding highlights the importance of monitoring eye health for overall survival.

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Area of Science:

  • Ophthalmology
  • Epidemiology
  • Public Health

Background:

  • The Beijing Eye Study investigated the link between retinopathy and mortality in a population-based cohort.
  • Retinopathy was diagnosed using the Early Treatment of Diabetic Retinopathy Study (ETDRS) criteria.

Purpose of the Study:

  • To assess the association between retinopathy and mortality in adult Chinese.
  • To identify risk factors for increased mortality in this population.

Main Methods:

  • A cohort of 4,391 subjects was initially examined in 2001 for retinopathy.
  • Fundus photographs were used to grade retinopathy according to ETDRS criteria.
  • A follow-up examination was conducted in 2006 to determine mortality.

Main Results:

  • Mortality rate was significantly higher in subjects with retinopathy (6.3%) compared to those without (3.0%).
  • Retinopathy was independently associated with increased mortality (OR: 2.13; 95% CI: 1.25, 3.62).
  • Other significant mortality risk factors included older age, male gender, and rural living.

Conclusions:

  • Retinopathy, by ETDRS criteria, is a risk factor for increased mortality in adult Chinese.
  • Age, gender, and geographic region also significantly influence mortality risk.