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Motor neuron disease associated with multiple myeloma
Filiz Koc1, Semra Paydas, Deniz Yerdelen
1Department of Neurology, Cukurova University, Faculty of Medical, Adana, Turkey. koc.filiz@gmail.com
The International Journal of Neuroscience
|February 27, 2008
Summary
This case study highlights a rare association between Motor Neuron Disease (MND) and Multiple Myeloma (MM). The patient developed MND while in remission for MM, suggesting a potential link between these conditions.
Area of Science:
- Neurology
- Hematology
- Oncology
Background:
- The association between Motor Neuron Diseases (MND) and lymphoproliferative disorders (LPDs) is known.
- The specific link between MND and Multiple Myeloma (MM) is infrequently documented.
Observation:
- A case report of a 75-year-old male patient with both MM and MND.
- The patient was diagnosed with MND during complete remission of MM.
Findings:
- The patient's MM was in remission at the time of MND diagnosis.
- The patient ultimately succumbed to progressive MND.
Implications:
- This case suggests a potential, though rare, association between MND and MM.
- Further research is warranted to explore the pathogenetic mechanisms linking these conditions, potentially involving immune responses or autoantibodies against motor neurons.
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