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Updated: Jul 7, 2026

The Mouse Forced Swim Test
Published on: January 29, 2012
Effect of pilopool on forced swimming test in mice
Hyun-Na Koo1, Jae-Young Um, Hyung-Min Kim
1Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University, Seoul, Republic of Korea.
Abstract:
Pilopool is composed of high molecular weight water-soluble chitosan, Allium sativum L. extract, mushroom extract, Dioscorea Batatas D., and purple bamboo salt. This study investigated the effect of Pilopool on performance of forced swimming test (FST). First, the immobility time was decreased in Pilopool-fed group in comparison with control group on FST. In blood serum, the contents of creatine kinase and lactic dehydrogenase were decreased and the contents of glucose and total protein were increased. The results predict a potential benefit of Pilopool as an anti-fatigue agent and for improving physical stamina.

