Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Proteinuria in essential hypertension.

S Sagar1, Rosangluaia, S Kumari

  • 1Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh.

The Indian Journal of Medical Research
|February 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deciphering a pathogen's evolution: a two-decade longitudinal study reveals virulence shifts and identifies durable Pm genes against Himalayan Blumeria graminis f. sp. tritici populations.

Stress biology·2026
Same author

Characterization of novel polysulfide polymer coated fly ash and its application in mitigating diffusion of contaminants.

Environmental pollution (Barking, Essex : 1987)·2024
Same author

Entropy generation minimization of higher-order endothermic/exothermic chemical reaction with activation energy on MHD mixed convective flow over a stretching surface.

Scientific reports·2022
Same author

Hemodynamical analysis of MHD two phase blood flow through a curved permeable artery having variable viscosity with heat and mass transfer.

Biomechanics and modeling in mechanobiology·2022
Same author

Bioremediation: an alternative approach for detoxification of polymers from the contaminated environment.

Letters in applied microbiology·2021
Same author

Impact of COVID-19 on cancer care in India: a cohort study.

The Lancet. Oncology·2021

Proteinuria, a marker of kidney damage, is common in essential hypertension. Abnormal proteinuria levels correlate with more severe hypertension complications like hypertensive retinopathy and renal insufficiency.

Area of Science:

  • Nephrology
  • Cardiology
  • Internal Medicine

Background:

  • Essential hypertension is a significant risk factor for cardiovascular and renal diseases.
  • Proteinuria is a recognized indicator of kidney damage in hypertensive individuals.
  • Understanding the prevalence and correlates of proteinuria is crucial for managing hypertension.

Purpose of the Study:

  • To investigate the prevalence and degree of proteinuria in patients with essential hypertension.
  • To identify correlations between proteinuria and indicators of end-organ damage in hypertension.

Main Methods:

  • A cohort of 100 essential hypertensive patients was studied.
  • Proteinuria was quantified using the modified biuret method (mg/1.73 M²/24 h).
  • Patients were categorized by hypertension severity, and associations with renal insufficiency, hypertensive retinopathy (grades III-IV), and left ventricular hypertrophy (LVH) on ECG were assessed.

Related Experiment Videos

Main Results:

  • Abnormal proteinuria was detected in 15% of mild, 27% of moderate, and 71% of severe accelerated/malignant hypertensive patients.
  • Proteinuria levels were significantly higher in patients with renal insufficiency (P < 0.001) and severe hypertensive retinopathy.
  • Abnormal proteinuria was strongly associated with the presence of LVH (42.3% vs 12.2%), severe retinopathy (30.8% vs 4.1%), and renal insufficiency (34.6% vs 0%).

Conclusions:

  • Proteinuria is a prevalent complication in essential hypertension, increasing with disease severity.
  • Elevated proteinuria is a significant marker for advanced hypertensive end-organ damage, including renal insufficiency, retinopathy, and LVH.
  • Monitoring proteinuria is essential for risk stratification and management of hypertensive patients.