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Updated: Jul 7, 2026

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Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
Published on: September 20, 2016
[Lung cancer in Senegal]
A Niang1, A Bonnichon, K Ba-Fall
1Services médicaux, Hôpital Principal, Dakar, Sénégal.
Medecine Tropicale : Revue Du Corps De Sante Colonial
|February 28, 2008
Summary
Lung cancer incidence is rising in Africa. Chemotherapy improved median survival by 4 months, but high costs and late-stage diagnosis contribute to poor prognosis for lung cancer patients in Dakar.
Area of Science:
- Oncology
- Public Health
- Epidemiology
Context:
- Lung cancer incidence is rapidly increasing in Africa.
- The study focuses on patients treated at the Principal Hospital in Dakar, Senegal, between 2002 and 2007.
- Lung cancer presents a significant health challenge in Dakar.
Purpose:
- To analyze the clinical, therapeutic, and prognostic features of lung cancer patients in Dakar.
- To evaluate the effectiveness of chemotherapy in improving survival rates.
- To identify challenges in lung cancer management within the African socio-economic context.
Summary:
- A prospective study of 72 lung cancer patients in Dakar revealed a predominantly male demographic (88%) with a mean age of 59.2 years, often smokers.
- Histological diagnoses included squamous cell carcinoma, adenocarcinoma, and large-cell carcinoma, with most cases diagnosed at advanced stages (Grade IV).
- Chemotherapy, though feasible, was costly and inaccessible to many, yet significantly improved median survival by 4 months compared to symptomatic management alone.
Impact:
- The study highlights the need for accessible therapeutic standards adapted to the African socio-economic setting.
- Improved diagnostic capabilities, such as bronchial endoscopy and CT-guided biopsy, have increased histological diagnosis rates.
- Urgent implementation of anti-tobacco prevention policies is crucial to address the rising lung cancer burden.
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