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Atrial parasystole in left ventricular noncompaction: a morphofunctional study by echocardiography and magnetic

Cesare de Gregorio1, Gianluca Di Bella, Lorenzo Curtò

  • 1Cardiology Unit, University Hospital of Messina, Messina, Italy. cesaredegregorio@alice.it

Journal of Cardiovascular Medicine (Hagerstown, Md.)
|February 28, 2008
PubMed

Insights

Isolated left ventricular noncompaction, a cardiac genetic disorder, can manifest solely as atrial arrhythmias. This case highlights a rare presentation of ventricular noncompaction in a young woman.

Area of Science:

  • Cardiology
  • Genetics
  • Cardiac Morphology

Background:

  • Isolated left ventricular noncompaction (ILVNC) is an age-independent genetic cardiac disorder.
  • It arises from defects in endo-myocardial morphogenesis.
  • Diagnosis is typically noninvasive via echocardiography or cardiac magnetic resonance.

Observation:

  • A young woman presented with an unusual clinical manifestation of ILVNC.
  • Her primary and sole clinical sign was an atrial parasystole.
  • This contrasts with the more commonly reported atrial and ventricular arrhythmias.

Findings:

  • The case details the morphological and functional findings of ILVNC.
  • It emphasizes the potential for atypical presentations of this cardiac condition.
  • Atrial parasystole was the exclusive clinical indicator in this patient.

Implications:

  • This case expands the understanding of ILVNC's clinical spectrum.
  • It suggests that atrial parasystole should be considered in the differential diagnosis of ILVNC.
  • Further research into the genetic and morphogenetic underpinnings of varied ILVNC presentations is warranted.

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