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Developing role of magnetic resonance imaging in Crohn's disease

Michael F Lin1, Vamsidhar Narra

  • 1Mallinkrodt Institute of Radiology, Washington University in St Louis, Missouri, USA.

Current Opinion in Gastroenterology
|February 28, 2008
PubMed
Abstract

Insights

Magnetic resonance enterography (MRE) offers a radiation-free method for evaluating Crohn's disease. Advancements in MRI technology enable detailed assessment of disease extent and complications, providing a promising alternative to CT scans.

Area of Science:

  • Gastroenterology
  • Radiology
  • Medical Imaging

Background:

  • Diagnostic radiation from CT scans raises concerns for patients with inflammatory bowel disease, potentially increasing lymphoma risk.
  • Crohn's disease patients are often young, making cumulative radiation exposure a significant consideration.

Purpose of the Study:

  • To review recent advancements in magnetic resonance enterography (MRE) techniques.
  • To examine the role of MRI in evaluating Crohn's disease, particularly in light of radiation concerns.

Main Methods:

  • Utilizes recent progress in magnetic resonance technology and imaging protocols.
  • Incorporates improved coils, breath-hold sequences, and faster acquisition techniques for small bowel imaging.

Main Results:

  • MRI is now feasible for small bowel imaging, capable of depicting disease location, extent, and complications.
  • Current literature widely recognizes MRI as an excellent tool for characterizing transmural and extraluminal changes in Crohn's disease.

Conclusions:

  • The primary advantage of MRE is its lack of ionizing radiation, crucial for young Crohn's disease patients.
  • Despite potential limitations like susceptibility to air and motion, MRI shows promise as a CT alternative for monitoring Crohn's disease progression and treatment response.

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