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Updated: Jul 7, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Atrial septal defect in adults.
1Adult Cardiology Department, National Institute of Cardiology of Mexico, Mexico City, Mexico.
Surgical closure of atrial septal defects (ASDs) in adults over 40 offers better outcomes than medical management alone. Early intervention is recommended, even with minimal symptoms, for optimal results.
Area of Science:
- Cardiology
- Adult Congenital Heart Disease
Background:
- Atrial septal defect (ASD) treatment in adults over 40 is debated.
- Understanding long-term outcomes and optimal closure strategies is crucial.
Purpose of the Study:
- To evaluate the natural history of untreated ASDs in adults.
- To compare surgical closure versus no closure for adult ASDs.
- To compare surgical versus transcatheter occlusion methods for adult ASDs.
Main Methods:
- Analysis of patient data across different subgroups.
- Comparison of natural history, surgical closure, and transcatheter occlusion.
- Evaluation of outcomes in adults aged <40 and >40 years.
Main Results:
- Surgical treatment yielded superior results compared to medical treatment alone.
- Early intervention, even with minimal symptoms, is advised.
- Transcatheter occlusion showed comparable safety and efficacy to surgery, with no significant difference in younger adults.
Conclusions:
- Surgical closure is recommended for adult ASDs, preferably performed early.
- Transcatheter occlusion is a safe and effective alternative, particularly in younger adults.
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