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Related Experiment Video

Updated: Jul 7, 2026

Intravital Longitudinal Imaging of Vascular Dynamics in the Calvarial Bone Marrow

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Published on: April 11, 2025

Median defect in the skull.

R Singh¹, M Bandyopadhyay

¹Department of Anatomy, Calcutta National Medical College, 32 Gorachand Road, Kolkata 700014, West Bengal, India. singhroyana@rediffmail.com

Singapore Medical Journal

|February 28, 2008

Summary

This summary is machine-generated.

A rare median defect was found in the nasal root of a human skull. This anatomical variation may stem from developmental abnormalities in the prenasal space and nasal capsule.

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Area of Science:

Anatomy
Embryology
Osteology

Background:

Anatomical variations can provide insights into developmental processes.
Understanding skull development is crucial for diagnosing congenital anomalies.

Observation:

A median defect was observed at the root of the nose in a 44-year-old female cadaver's dried skull.
The nasal bones, lacrimal bones, and maxillary bones showed deformities.

Findings:

The median nasal defect is hypothesized to result from abnormalities in the fonticulus frontalis, prenasal space, and interorbitonasal nasal capsule.
Ossification defects in the maxilla, lacrimal, and frontal bones are also implicated.

Implications:

This case highlights potential developmental pathways for craniofacial anomalies.
Further research into the prenasal space and nasal capsule development is warranted.
Such findings can aid in the diagnosis and understanding of congenital nasal and orbital malformations.