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Parent-controlled analgesia in children undergoing cleft palate repair
Seung Ho Choi1, Woo Kyung Lee, Sung Jin Lee
1Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea.
Insights
This study determined an effective fentanyl dose for parent-controlled analgesia (PrCA) in children after cleft palate repair. The optimal basal infusion rate of 0.63 microgram/kg/hr achieved high parent satisfaction with postoperative pain management.
Area of Science:
- Pediatric Anesthesiology
- Pain Management
- Surgical Recovery
Background:
- Postoperative pain management in pediatric cleft palate repair requires effective and safe analgesia.
- Parent-controlled analgesia (PrCA) offers a patient-centered approach to managing pain in young children.
- Fentanyl is a potent opioid commonly used for analgesia, but optimal dosing for PrCA needs definition.
Purpose of the Study:
- To identify an optimal basal infusion dose of fentanyl for parent-controlled analgesia (PrCA) in pediatric cleft palate repair.
- To assess the level of parental satisfaction with the PrCA modality for postoperative pain control.
Main Methods:
- An up-and-down method was employed to determine the effective dose of fentanyl (ED50 and ED95) for PrCA.
- Thirty children (6 months–2 yr) received fentanyl via PrCA post-cleft palate repair.
- Parents were educated on PrCA device use, pain scoring, and adverse effect monitoring.
Main Results:
- The estimated 50% effective dose (ED50) of fentanyl was 0.63 microgram/kg/hr.
- The estimated 95% effective dose (ED95) of fentanyl was 0.83 microgram/kg/hr.
- Eighty-seven percent of parents reported satisfaction with the PrCA method.
Conclusions:
- Parent-controlled analgesia with fentanyl at a basal infusion rate of 0.63 microgram/kg/hr is effective for postoperative pain management in children undergoing cleft palate repair.
- PrCA with this fentanyl regimen demonstrates a high level of parental satisfaction.
- This approach provides a safe and effective option for pediatric postoperative pain control.
Abstract:
The aims of this study were to find an optimal basal infusion dose of fentanyl for parent-controlled analgesia (PrCA) in children undergoing cleft palate repair and the degree of parents' satisfaction with PrCA. Thirty consecutive children between 6 months and 2 yr of age were enrolled. At the end of surgery, a PrCA device with a basal infusion rate of 2 mL/hr and bolus of 0.5 mL with lockout time of 15 min was applied. Parents were educated in patient-controlled analgesia (PCA) devices, the Wong Baker face pain scoring system, and monitoring of adverse effects of fentanyl. Fentanyl was infused 0.3 microgram/kg/hr at first, and we obtained a predetermined fentanyl regimen by the response of the previous patient to a larger or smaller dose of fentanyl (0.1 microgram/kg/hr as the step size), using an up-and-down method. ED50 and ED95 by probit analysis were 0.63 microgram/kg/hr (95% confidence limits, 0.55-0.73 microgram/kg/hr) and 0.83 microgram/kg/hr (95% confidence limits, 0.73-1.47 microgram/kg/hr), respectively. Eighty seven percent of the parents were satisfied with participating in the PrCA modality. PrCA using fentanyl with a basal infusion rate of 0.63 microgram/kg/hr can be applied effectively for postoperative pain management in children undergoing cleft palate repair with a high level of parents' satisfaction.
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