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Related Concept Videos

Vaporization01:18

Vaporization

The physical form of a substance changes by changing its temperature. For example, raising the temperature of a liquid causes the liquid to vaporize (convert into vapor). The process is called vaporization—a surface phenomenon. For vaporization to occur, kinetic energy must be greater than the intermolecular forces that keep molecules bonded. The amount of energy needed to vaporize a quantity of liquid at a given pressure and a constant temperature is called the heat of vaporization. When...
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without causing...
Acute Respiratory Failure-I01:21

Acute Respiratory Failure-I

Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Atelectasis II: Pathophysiology01:10

Atelectasis II: Pathophysiology

Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...

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Related Experiment Video

Updated: Jul 7, 2026

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation
09:03

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

Published on: August 15, 2018

Evaporated liquid nitrogen-induced asphyxia: a case report.

Dong Hoon Kim1, Hyung Jong Lee

  • 1Department of Pathology, Pohang Hospital, Dongguk University College of Medicine, Pohang, Korea. withdhk@naver.com

Journal of Korean Medical Science
|February 28, 2008
PubMed
Summary

A postgraduate student died from asphyxia due to evaporated liquid nitrogen in an unsealed underground area. Rapid oxygen depletion in the confined space led to fatal hypoxemia.

Area of Science:

  • Forensic Science
  • Environmental Health & Safety

Background:

  • A fatality occurred in a confined underground space involving liquid nitrogen.
  • The incident involved an improperly managed liquid nitrogen cylinder and Dewar flask setup.

Observation:

  • A 27-year-old postgraduate student was found deceased in an unsealed underground dry area.
  • External and internal examinations revealed no trauma, but petechiae were present in the conjunctivae and periorbital skin.
  • Atmospheric analysis showed rapid oxygen depletion, falling to 12.0% within minutes and reaching 4.2% within 20 minutes.

Findings:

  • The primary cause of death was determined to be asphyxia.
  • Evaporated liquid nitrogen rapidly displaced oxygen in the confined space, leading to a hazardous atmosphere.
  • The setup with an open cylinder connected to a flask facilitated rapid gas evaporation and oxygen displacement.

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Induction of Cerebral Arterial Gas Embolism in Rat

Published on: October 18, 2024

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The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation
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The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

Published on: August 15, 2018

Induction of Cerebral Arterial Gas Embolism in Rat
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Induction of Cerebral Arterial Gas Embolism in Rat

Published on: October 18, 2024

Implications:

  • Highlights the extreme dangers of asphyxiation from inert gas displacement in confined spaces.
  • Underscores the critical need for stringent safety protocols when handling cryogenic liquids like liquid nitrogen.
  • Emphasizes the importance of adequate ventilation and atmospheric monitoring in areas where inert gases are used or stored.