Related Experiment Video
Updated: Jul 7, 2026

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
Published on: September 16, 2025
Clinical comparison of the Icare tonometer and Goldmann applanation tonometry
Nima Pakrou1, Tim Gray, Richard Mills
1Department of Ophthalmology, Flinders Medical Centre, Bedford Park, South Australia. nima.pakrou@eyeandear.org.au
Purpose:
To compare a new method of intraocular pressure (IOP) measurement, using the Icare tonometer, with Goldmann applanation tonometry (GAT).
Patients And Methods:
Two observers obtained IOP readings in 292 eyes (143 right and 149 left) of 153 subjects, using the Icare without topical anesthetic. A GAT reading was subsequently obtained by a consultant ophthalmologist, without the knowledge of the Icare readings. Central corneal thickness (CCT) was obtained on all eyes with ultrasound pachymetry. Patient comfort after IOP measurement was assessed in a consecutive subset of patients.
Results:
The intraclass correlation coefficient between the 2 modalities of IOP measurement was r=0.95 for the right and r=0.93 for the left eye. The mean difference (Icare-GAT) between the IOP measured by the 2 methods was 0.4 mm Hg in the right eye (SD 3.0, 95% confidence interval -5.5 to 6.3), and 0.8 mm Hg in the left eye (SD 3.0, confidence interval -4.7 to 6.2). GAT measurements did not vary with CCT [correlation coefficient=0.09 (P=0.25) right and 0.14 (P=0.09) left eyes]. However, IOP measured with Icare tonometry increased with increasing CCT [correlation coefficient=0.16 (P=0.05) right and 0.21 (P=0.01) left eyes]. For every 100-microm increase in CCT, the difference (Icare-GAT) increased by 1 mm Hg. Of the 38 consecutive patients surveyed, 28 (73.7%) rated the Icare more comfortable than GAT, with only 2 (5.3%) rating it less comfortable (P<0.001).
Conclusions:
There is good correlation between the 2 methods of IOP measurement, even at extremes of IOP. The Icare instrument was easy to use and recorded rapid and consistent readings with minimal training. It seems to be more comfortable than GAT and obviates the need for topical anesthesia.
Related Concept Videos
Comparison Tests
Equipments Used To Measure Blood Pressure
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
Comparing Experimental Results: Student's t-Test
Assessment of blood pressure in brachial artery(two-step method)
Multiple Comparison Tests
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
Temperature Measurement Sites
Oral: When assessing oral temperature, the thermometer tip should be placed under the tongue in the posterior sublingual pocket. It offers accurate readings and can be...
