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Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles
Published on: March 13, 2017
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[A rapid, multiplexed new technology xMAP liquid chip for detection and identification of pathogens]
1College of Animal Science and Technology, Northwest A & F University, Yangling 712100, China. hurui-a@126.com
Wei Sheng Yan Jiu = Journal of Hygiene Research
|February 29, 2008
Summary
The xMAP liquid chip is an advanced microsphere-based biochip technology enabling simultaneous detection of up to 100 analytes. This high-sensitivity technology offers excellent reproducibility for biological molecule analysis.
Area of Science:
- Biotechnology
- Analytical Chemistry
- Molecular Biology
Context:
- Microsphere-based biochip technology
- Developed by Luminex Corporation
- Simultaneous detection of multiple analytes
Purpose:
- To introduce and highlight the capabilities of the xMAP liquid chip technology
- To compare its advantages over traditional chip formats
- To showcase its applications in biological molecule analysis
Summary:
- The xMAP liquid chip technology utilizes microspheres for multiplexed detection of up to 100 analytes in a single reaction.
- It offers significant advantages including high sensitivity (0.01 pg), excellent reproducibility (CV < 5%), and a wide dynamic range (0.2 - 32000 pg/ml).
- This technology is particularly effective for the analysis and identification of nucleic acids, proteins, and other biological molecules.
Impact:
- Enables high-throughput, sensitive, and reproducible analysis of biological samples.
- Provides a versatile platform for various applications in life sciences research and diagnostics.
- Advances the field of biochip technology with its multiplexing capabilities and performance metrics.
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