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Related Concept Videos

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia01:30

Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia

Depending on the target organ, local anesthetics (LAs) can be administered via various routes. In surface anesthesia, LAs are applied directly to the surface of the skin or mucous membranes. It is widely used for topical skin numbing before venipuncture or minor surgical procedures. Commonly used surface local anesthetics are lidocaine or benzocaine sprays or creams. Surface anesthesia occurs within 5 minutes and lasts for about 60 minutes. One of the main disadvantages of topical anesthesia is...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...

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Updated: Jul 7, 2026

Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat
08:05

Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat

Published on: November 21, 2025

[Analgesia for wound dressing by continuous peripheral nerve block].

J P Lecoq1, D Jacquemin, M Lamy

  • 1Service d'Anesthésie-Réanimation, CHU Sart Tilman, Liège, Belgique. jplecoq@chu.ulg.ac.be

Revue Medicale De Liege
|February 29, 2008
PubMed
Summary

Continuous peripheral nerve blocks effectively managed chronic pain and improved wound care tolerance in a patient with a venous ulcer. This technique offers favorable pain relief and wound healing benefits.

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Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds
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Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds

Published on: October 20, 2012

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Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat
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Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds
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Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds

Published on: October 20, 2012

Area of Science:

  • Pain Management
  • Vascular Surgery
  • Regenerative Medicine

Background:

  • Chronic venous ulcers present significant challenges in pain management and wound healing.
  • Standard analgesics often prove insufficient and cause adverse effects in patients with chronic pain.
  • Surgical interventions for venous ulcers require effective pain control to ensure patient tolerance and optimize outcomes.

Observation:

  • A patient with a circumferential venous ulcer experienced severe chronic pain refractory to conventional treatments.
  • The patient underwent surgical treatment involving continuous aspiration dressing and skin grafting.
  • A double continuous peripheral nerve block (femoral and sciatic) was implemented to manage pain during wound care.

Findings:

  • The peripheral nerve block technique provided significant and favorable antalgic results, improving patient tolerance to wound dressing.
  • The study describes indications and techniques for peripheral nerve blocks, including electrostimulation and echo-guidance.
  • Literature data on infectious risks associated with catheters near cutaneous wounds were reviewed.

Implications:

  • Continuous peripheral nerve blocks are a relevant strategy for managing chronic pain associated with complex wounds.
  • This approach may positively influence wound trophicity and healing processes.
  • Peripheral nerve blocks offer a promising alternative for improving patient outcomes in vascular surgery and chronic wound care.