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Clostridium difficile: the increasingly difficult pathogen.

Aurora Pop-Vicas, Marguerite A Neill

    Critical Care (London, England)
    |February 29, 2008
    PubMed
    Summary
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    The epidemiology of Clostridium difficile infection is changing due to a hypervirulent strain. Clinicians must stay updated on diagnosing and treating this increasingly common disease.

    Area of Science:

    • Infectious Diseases
    • Epidemiology
    • Microbiology

    Background:

    • The epidemiology of Clostridium difficile infection (CDI) is shifting.
    • The emergence of a hypervirulent North American Pulsefield type 1 strain is driving these changes.

    Discussion:

    • This hypervirulent strain is contributing to an increased incidence of CDI.
    • Healthcare professionals will encounter CDI more frequently in clinical practice.

    Key Insights:

    • A specific hypervirulent strain of Clostridium difficile is altering infection patterns.
    • Increased clinical encounters with CDI are anticipated.

    Outlook:

    • Clinicians need to be aware of the evolving diagnostic criteria for CDI.

    Related Experiment Videos

  • Updated treatment guidelines for Clostridium difficile infection are essential for effective patient management.