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Nucleotide sequence of a cDNA for the alpha subunit of human mitochondrial ATP synthase
1Department of Anatomy and Cellular Biology, Tufts University Health Science Schools, Boston, MA 02111.
Biochimica Et Biophysica Acta
|July 23, 1991
Abstract:
A full length cDNA clone of the alpha subunit of mitochondrial ATP synthase (EC 3.6.1.34) has been isolated from a cDNA library prepared from LX-1 human tumor cells in the lambda-Zap vector. The clone is 1883 base pairs (bp) in length and contains a 1659 bp open reading frame encoding a polypeptide of 553 residues. The deduced amino acid sequence is highly homologous to ATP synthase from several other species.