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Related Concept Videos

Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
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Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
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Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

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Related Experiment Video

Updated: Jul 7, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

Bacteraemic spondylodiscitis caused by Enterococcus hirae.

E Canalejo1, R Ballesteros, J Cabezudo

  • 1Department of Internal Medicine, Hospital de Fuenlabrada, Camino del Molino, 2, 28942, Fuenlabrada, Madrid, Spain. ecanalejo@jazzfree.com

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
|February 29, 2008
PubMed
Summary

Enterococcus hirae is a rare cause of human infection. This report details the first case of E. hirae spondylodiscitis with associated abscesses, highlighting the need for awareness of this pathogen.

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Last Updated: Jul 7, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Clinical Medicine

Background:

  • Enterococcus hirae is a bacterium typically found in animals, rarely causing human infections.
  • Human infections with E. hirae are exceptionally uncommon, with limited documented cases.
  • Spondylodiscitis, an infection of the spine and intervertebral discs, can have severe complications.

Observation:

  • A 55-year-old male patient with diabetes mellitus presented with symptoms suggestive of spinal infection.
  • Diagnostic imaging revealed spondylodiscitis complicated by an anterior epidural abscess and multiple psoas abscesses.
  • Cultures identified the causative agent as Enterococcus hirae.

Findings:

  • This case represents the first documented instance of Enterococcus hirae causing spondylodiscitis in a human.
  • The patient required surgical intervention despite receiving appropriate antimicrobial treatment.
  • This finding expands the known spectrum of human infections caused by E. hirae.

Implications:

  • Clinicians should consider Enterococcus hirae in the differential diagnosis of rare spinal infections, particularly in immunocompromised patients.
  • This case underscores the importance of microbiological identification for guiding effective treatment strategies.
  • Further research is needed to understand the pathogenicity and clinical manifestations of E. hirae in humans.