Related Experiment Video
Updated: Jul 7, 2026

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
The effect of heat-moisture exchanger and closed-circuit technique on airway climate during desflurane anesthesia
Chih-Cherng Lu1, Shung-Tai Ho, Wen-Jinn Liaw
1Department of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Purpose:
We assessed whether closed-circuit anesthesia (CCA) could provide a more favorable airway climate than semi-closed anesthesia (SCA), and we also determined the beneficial effect of heat moisture exchangers (HMEs) on the preservation of airway climate during desflurane anesthesia.
Methods:
Forty patients scheduled for colorectal surgery (n = 10 for each group) were randomized to receive a fresh gas flow of 250 or 3000 ml.min(-1) with or without HMEs. Anesthesia was maintained by adjusting the inspired concentration of 6% desflurane. Absolute moisture and temperature of inspired gases were measured as the baseline value first at 5 min after tracheal intubation, and then at 10, 20, 45, 60, 90, and 120 min after the induction of anesthesia.
Results:
At 120 min, the inspiratory humidity and temperature were higher in CCA than in SCA. The HME led to major improvements of the humidity (from 22.1 to 35.7 mg H(2)O.l(-1)) and temperature (from 23.6 degrees C to 31.5 degrees C) of anesthetic gases in the CCA group.
Conclusion:
CCA was much more advantageous than SCA for maintaining the patient's airway climate during the 2-h study. The beneficial effect of HME on the airway climate should be emphasized, especially in patients undergoing general anesthesia.
Related Concept Videos
Inhalational Anesthetics: Overview
Cardiopulmonary Resuscitation II: ACLS Airway Management
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Endotracheal Tube Extubation
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals.
