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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
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Published on: January 18, 2018

Rescue use of tirofiban for acute carotid in-stent thrombosis

Kwon Duk Seo1, Kee Oog Lee, Dong Joon Kim

  • 1Department of Neurology, Yonsei University College of Medicine 146-92 Dogok-dong, Kangnam-gu, Seoul 135-720, Korea.

Yonsei Medical Journal
|February 29, 2008
PubMed

Insights

Acute in-stent thrombosis after carotid artery stenting is a rare complication. This case highlights successful treatment using intravenous tirofiban, a glycoprotein IIb/IIIa receptor inhibitor.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Vascular Surgery

Background:

  • Extracranial carotid artery stenosis is commonly treated with carotid artery stenting.
  • In-stent thrombosis (IST) is a rare but serious complication following this procedure.
  • Prompt diagnosis and management are crucial to prevent adverse outcomes.

Observation:

  • A 64-year-old male presented with acute in-stent thrombosis.
  • The event occurred immediately after stent placement and post-balloon dilatation for carotid stenosis.
  • The patient experienced symptoms indicative of acute thrombosis.

Findings:

  • The acute in-stent thrombosis was diagnosed promptly.
  • Successful treatment was achieved with intravenous tirofiban.
  • Tirofiban, a glycoprotein IIb/IIIa receptor inhibitor, effectively resolved the thrombosis.

Implications:

  • This case underscores the importance of vigilance for IST after carotid stenting.
  • Intravenous tirofiban is an effective therapeutic option for acute IST.
  • Further research may elucidate optimal management strategies for IST in carotid artery stenting.

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