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Giant primary mesenteric liposarcoma: a rare case report.

Nazoora Khan1, Nishat Afroz, Uroos Fatima

  • 1Department of Pathology, Jawahar Lal Nehru Medical College, Aligarh Muslim University, Aligarh.

Indian Journal of Pathology & Microbiology
|March 1, 2008
PubMed
Summary

This case report details a rare, large primary mesenteric liposarcoma in a 55-year-old man. The tumor, weighing 8.5 kg, presented with mixed histological features, highlighting diagnostic challenges and rarity.

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Area of Science:

  • Oncology
  • Surgical Pathology

Background:

  • Primary mesenteric liposarcoma is a rare malignant mesenchymal tumor.
  • These tumors often present at a substantial size, posing diagnostic and surgical challenges.

Observation:

  • A 55-year-old man presented with a large mesenteric mass, initially suspected to be a cyst.
  • Laparotomy revealed two masses totaling 8.5 kg, with diameters of 19 cm and 14 cm.
  • Fine-needle aspiration cytology (FNAC) was inconclusive due to insufficient cellularity.

Findings:

  • Histopathology confirmed atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLS).
  • The tumor exhibited a mixed histological pattern, including lipoma-like, sclerosing, and myxoid areas.
  • Prognosis is influenced by anatomical location and histological subtype.

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Implications:

  • This case underscores the importance of considering rare tumors like mesenteric liposarcoma in large abdominal masses.
  • The significant size and mixed histology of this tumor present a unique clinical and pathological scenario.
  • Accurate histopathological classification is crucial for determining prognosis and guiding patient management.