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Related Concept Videos

Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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Genomic DNA in Eukaryotes

Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
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Genome Annotation and Assembly

The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
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Fruit Development, Structure, and Function

Fruits form from a mature flower ovary. As seeds develop from the ovules contained within, the ovary wall undergoes a series of complex changes to form fruit. In some fruits, such as soybeans, the ovary wall dries; in other fruits, such as grapes, it remains fleshy. In some cases, organs other than the ovary contribute to fruit formation; such fruits are called accessory fruits.

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Related Experiment Video

Updated: Jul 7, 2026

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
10:40

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine

Published on: December 22, 2017

VitisExpDB: a database resource for grape functional genomics.

Harshavardhan Doddapaneni1, Hong Lin, M Andrew Walker

  • 1USDA-ARS, San Joaquin Valley Agricultural Science Center, 9611 So. Riverbend Ave, Parlier, CA 93648, USA. harsha@fresno.ars.usda.gov <harsha@fresno.ars.usda.gov>

BMC Plant Biology
|March 1, 2008
PubMed
Summary
This summary is machine-generated.

VitisExpDB is a new online database offering genomic resources for Vitaceae family species. This comprehensive resource aids in grape gene functional analysis and genome annotation.

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Area of Science:

  • Genomics
  • Bioinformatics
  • Plant Science

Background:

  • The Vitaceae family encompasses diverse grape species adapted to various climates.
  • Recent advancements have yielded functional genomic data for multiple Vitis species, including Vitis vinifera.
  • A need exists for a centralized, comprehensive data source for Vitaceae genomics.

Purpose of the Study:

  • To develop a comprehensive web-based data resource for the Vitaceae family.
  • To integrate and provide access to expressed sequence tag (EST) and gene expression data for various grape species.

Main Methods:

  • Developed VitisExpDB, a MySQL-PHP relational database.
  • Housed approximately 320,000 annotated EST sequences from 8 Vitis species/hybrids.
  • Incorporated gene expression data, including 14 processed microarray profiles and a gene expression chip dataset.
  • Implemented a user-friendly web interface with bioinformatics tools for data retrieval and analysis.

Main Results:

  • The database contains annotated ESTs, gene expression profiles, and homology information across Vitis species.
  • Includes data on probe sequences, gene annotation, and phylogenetic relationships.
  • Features include metabolic pathway mapping for expression data and user submission capabilities.

Conclusions:

  • VitisExpDB serves as a valuable genomic resource for the grape research community.
  • Facilitates functional gene analysis, grape genome annotation, and gene function identification.
  • The database is accessible online at http://cropdisease.ars.usda.gov/vitis_at/main-page.htm.