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Updated: Jul 7, 2026
08:21
Dissection of the Mouse Pancreas for Histological Analysis and Metabolic Profiling
Published on: August 19, 2017
Pancreatic incidentalomas: clinical and pathologic spectrum.
Matias Bruzoni1, Elizabeth Johnston, Aaron R Sasson
1Surgical Oncology Department, University of Nebraska Medical Center, Omaha, NE 68198-4030, USA.
American Journal of Surgery
|March 1, 2008
Summary
Pancreatic incidentalomas, or lesions found incidentally, are common and often detected via CT scans. Prompt surgical evaluation is recommended for these pancreatic abnormalities.
Area of Science:
- Gastroenterology
- Oncology
- Radiology
Background:
- Incidental abnormalities are increasingly detected in medical imaging.
- The clinical outcomes and pathology of pancreatic incidentalomas remain under-characterized.
Purpose of the Study:
- To characterize the pathology and clinical outcomes of patients with incidentally detected pancreatic lesions.
Main Methods:
- Retrospective review of 356 patients with pancreatic abnormalities (August 2001 - June 2007).
- Collection of clinical and pathological data for patients with incidental pancreatic lesions detected via imaging.
Main Results:
- Fifty-seven pancreatic incidentalomas were identified, 90% by computed axial tomography (CT).
- Common indications for imaging included genitourinary symptoms and cancer surveillance.
- Lesions were 60% solid and 40% cystic; common diagnoses included ductal adenocarcinoma, neuroendocrine tumors, and serous cystadenoma. Advanced disease was noted in 15 patients.
Conclusions:
- Incidental pancreatic lesions represent a significant patient subgroup.
- These lesions are frequent and necessitate prompt surgical evaluation.
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