Risk factors and neurological consequences of syncopes induced by internal carotid artery angioplasty
Insights
Syncope after carotid angioplasty (CA) is linked to plaque length and location. However, this syncope does not increase the risk of stroke or death during the procedure.
Area of Science:
- Neurology
- Cardiovascular Medicine
- Interventional Cardiology
Background:
- Syncope and carotid sinus reactions (CSR) are common during carotid angioplasty (CA).
- Understanding risk factors and neurological outcomes of CA-induced syncope is crucial.
Purpose of the Study:
- To investigate risk factors for syncope during CA.
- To determine the neurological consequences of CA-induced syncope.
Main Methods:
- 359 patients undergoing CA were assessed.
- Cerebrovascular reserve and continuous EEG monitoring were performed.
- Impact of vascular risk factors, plaque characteristics, and procedural factors on CSR and syncope was analyzed.
Main Results:
- CSR occurred in 62.7% and syncope in 18.0% of procedures.
- Syncope was associated with longer plaques, carotid bifurcation location, contralateral stenosis, and protection device use.
- TIA was more frequent in syncopal patients, but stroke/death rates were similar.
Conclusions:
- Syncope during CA is more common with specific plaque characteristics (long, bifurcation location).
- Syncope does not elevate periprocedural complication rates like stroke or death.
Background And Purpose:
Syncope and carotid sinus reactions (CSR) occur frequently in patients undergoing carotid angioplasty (CA). We investigated risk factors and the neurological consequences of carotid sinus syncope induced by CA.
Methods:
We examined 359 consecutive patients. Patients underwent assessment of cerebrovascular reserve before CA and continuous electroencephalographical monitoring during the procedure. We examined the impact of vascular risk factors, cerebral hemodynamics, characteristics of plaque, and procedural modality on the incidence of CSR and syncope. The effect of syncopes on periprocedural complication rates was also investigated.
Results:
CSR and syncope occurred in 62.7% and 18.0% of the procedures, respectively. The occurrence of CSR during angioplasty was significantly associated with the appearance of syncope. The incidence of syncope was significantly higher in longer plaques located in the carotid bifurcation, in the presence of contralateral carotid stenosis, or when protection devices were used. Although TIA during CA was more common in syncopal patients, stroke or death rates were similar in the 2 groups.
Conclusions:
Syncope occurs more frequently in patients with long plaques proximal to the carotid bifurcation, but it does not increase the periprocedural complications rate.
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