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Updated: Jul 7, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Anterior cruciate ligament reconstruction in adolescents: a survivorship analysis
Wudbhav N Sankar1, Robert B Carrigan, John R Gregg
1Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Abstract:
There are few reports on the longevity of anterior cruciate ligament (ACL) reconstruction in adolescents. In the study reported here, we performed a survivorship analysis of our experience with ACL reconstructions in adolescents. We retrospectively reviewed the cases of 276 consecutive patients (girls' bone age, > 13 years; boys' bone age, > 14 years; chronological age, < 18 years) who underwent primary ACL reconstruction. All patients underwent transphyseal ACL reconstruction with Achilles tendon soft-tissue allograft using the same technique. Twenty-nine patients (10.5%) were excluded or lost to follow-up. Mean follow-up of the remaining 247 patients was 6.3 years (range, 2-10 years). Data were collected from charts and telephone interviews. Failure was defined as the report of symptomatic knee instability and/or revision ACL surgery. The Kaplan-Meier method showed that 1-year survivorship of ACL reconstruction was 96.4% and 5-year survivorship was 93.1%.