Related Experiment Video
Updated: Jul 7, 2026
09:53
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Diffuse cavernous haemangioma complicated with regional osteoporosis
Zafer Günendi1, Gülçin Kaymak Karatas, Vesile Sepici
1Department of Physical Medicine and Rehabilitation, Gazi University Faculty of Medicine, Besevler, Ankara, Turkey. zafergunendi@yahoo.com
Rheumatology International
|March 1, 2008
Summary
Cavernous hemangiomas, common benign tumors, can lead to rare complications like pathological fractures. This case highlights secondary regional osteoporosis as a potential complication in an 11-year-old patient.
Area of Science:
- Vascular Tumors
- Pediatric Oncology
- Skeletal Health
Background:
- Capillary and cavernous hemangiomas are common benign soft tissue tumors in infants.
- Cavernous hemangiomas feature larger vascular channels and often occur in deep dermal tissues.
- While many hemangiomas require no treatment, complications necessitate intervention.
Observation:
- An 11-year-old girl presented with a pathological fracture after minimal trauma.
- The fracture was suspected to be a result of secondary regional osteoporosis.
- The osteoporosis was potentially linked to a diffuse cavernous hemangioma.
Findings:
- Diffuse cavernous hemangioma can be associated with secondary regional osteoporosis.
- Pathological fractures are a rare but serious complication of such conditions.
- This case underscores the importance of considering bone health in patients with extensive hemangiomas.
Implications:
- Early recognition of potential complications like osteoporosis is crucial for managing hemangiomas.
- Further research is needed to understand the link between hemangiomas and secondary osteoporosis.
- This case may inform clinical practice regarding the skeletal evaluation of children with extensive cavernous hemangiomas.
Related Concept Videos
01:29Bone Disorders
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
01:19Cushing Syndrome II: Pathophysiology
Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...
01:29Blood and Nerve Supply to the Bones
Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
01:27Compact Bone
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
01:23Cirrhosis I: Introduction
Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
01:27Cryptococcal Meningitis
Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...