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Published on: May 9, 2019
[Study on extraction and drying of Ligusticum chuanxiong in Gan-ning Granule]
Yuan-Quan Ding1, Shao-Hui Wan, Qi-Tai Xu
1Medical Technical Stuff Training Base of Shenyang Military Area, Liaoning dalian 116017, China. 187dyq@163.com
Objective:
To find out the optimum extract process for Ligusticum chuanxiong in Gan-ning Granule, and studyed the methods of concentration and dry for the extract.
Method:
With the yield of ferulic acid as the assessment index, to optimize the 80% alcohol totalling, extracting times and circumfluence time for extract process by the orthogonal design, to optimize the inlet-air temperature, feed speed and density of feed for spry drying by the orthogonal design.
Result:
The optimum procedure was the ferulic acid were extracted for 1 hour with 3 times of 80% alcohol. While extracting times effected it most porminently. The optimal processing conditions of spry drying were inlet-air temperature 120 degrees C, feed speed 8.5 mL x min(-1) and density of feed 1.15, While feed speed effected it most porminently.
Conclusion:
The experimental results provide the basis for the extraction process and drying process of the ferulic acid in ligusticum chuanxiong.