[The biochemical composition of the bile and the function of the protective mucosal barrier in peptic ulcer patients]

The state of the protective mucosa barrier was studied in 87 patients with ulcer disease by means of determination of the level of PAS-positive substances and acid mucopolysaccharides in the gastric and duodenal mucosa. It was found that changes of the biochemical composition of the bile produced an essential influence on the reduction of protective properties of the gastroduodenal mucosa barrier, especially in the presence of gastroduodenal reflux.