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Updated: Jul 7, 2026
Characterization of a Novel Human Organotypic Retinal Culture Technique
Published on: June 9, 2021
[Erythropoietin concentrations in the vitreous body from patients with proliferative diabetic retinopathy]
V M Asensio-Sánchez1, V Gómez-Ramírez, I Morales-Gómez
1Hospital General, Medina del Campo, Valladolid, Spain. vasensio@hmdc.sacyl.es
Objective:
To measure erythropoietin (Epo) levels in the vitreous body from patients with proliferative diabetic retinopathy (PDR).
Patients And Methods:
Undiluted vitreous samples were obtained from 44 patients who had not undergone prior vitreous or intraocular surgery. Patients were divided into two groups: A (n= 24) patients with PDR and B (n= 20) patients with retinal detachment, preretinal macular membranes and macular holes. Epo was determined using radioimmunoassay.
Results:
Epo vitreous concentration in group A was 512 mU/mL (range 120-880) and in group B was 25.1 mU/mL (range 5.2-201) (p< 0.001).
Conclusions:
These results show that the concentration of Epo in the vitreous body was significantly higher in patients with PDR than in the control group.
