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Updated: Jul 7, 2026
10:33
Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis
Published on: December 17, 2021
[Two cases of syphilitic uveitis and HIV].
J Zarallo1, B Pastor, M Asencio
1Servicio de Oftalmología, Hospital Universitario La Paz, Madrid, Spain. jezarallo@hotmail.com
Archivos De La Sociedad Espanola De Oftalmologia
|March 4, 2008
Summary
Syphilis incidence is increasing, presenting atypical symptoms in HIV+ patients. Early diagnosis through clinical history is crucial, with macrolides as an alternative treatment for penicillin-allergic individuals.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Public Health
Background:
- Rising incidence of syphilis globally.
- HIV infection can alter syphilis presentation.
- Importance of considering co-infections in clinical practice.
Observation:
- Two cases of HIV-positive patients presenting with panuveitis.
- Case 1: Unilateral panuveitis with secondary syphilis signs.
- Case 2: Bilateral panuveitis, diagnosed with HIV and syphilis after prolonged treatment elsewhere.
Findings:
- Syphilis can manifest atypically in HIV-positive individuals.
- Thorough clinical history is essential for timely diagnosis.
- Successful treatment outcomes were achieved in both cases.
Implications:
- Highlights the need for heightened awareness of syphilis in HIV+ populations.
- Emphasizes the diagnostic value of detailed patient history.
- Suggests macrolides as a viable therapeutic option for penicillin-allergic patients with syphilis.
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