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A case of female epispadias
Julierut Tantibhedhyangkul1, Susannah D Copland, Andrea M Haqq
1Division of Reproductive Endocrinology and Fertility, Duke University Medical Center, Durham, North Carolina, USA.
Objective:
To present a case of unrecognized female epispadias.
Design:
Case report.
Setting:
University-based reproductive endocrinology and fertility clinic.
Patient(S):
A 16-year-old girl with epispadias, history of mild urinary incontinence, auditory neuropathy, and functional hyperandrogenism.
Intervention(S):
None.
Main Outcome Measure(S):
Peripheral blood array-based comparative genomic hybridization.
Result(S):
The patient was referred for evaluation of excessive weight gain, secondary amenorrhea, and abnormal external genitalia. Examination under anesthesia revealed bilateral labia minora hypertrophy, bifid clitoris, and a patulous urethra, consistent with female epispadias. Hormonal evaluation showed functional hyperandrogenism, and peripheral blood array-based comparative genomic hybridization showed no chromosomal deletions or duplications.
Conclusion(S):
Female epispadias is a rare abnormality, not commonly recognized by most practitioners. The diagnosis is supported by a history of urinary incontinence and physical findings of bifid clitoris and patulous urethra. The condition can have serious physical and psychological consequences leading to a gross disruption of social function.
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