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Updated: Jul 7, 2026

13:47
Development of Cell-type specific anti-HIV gp120 aptamers for siRNA delivery
Published on: June 23, 2011
Synthesis and anti-HIV1 biological activity of novel 5''-ATSAO compounds
Cyrille Tomassi1, Albert Nguyen Van Nhien, José Marco-Contelles
1Laboratoire des Glucides (UMR6219), Faculté des Sciences, Université de Picardie Jules Verne, 33 rue Saint Leu, 80039 Amiens, France.
Bioorganic & Medicinal Chemistry
|March 5, 2008
Abstract:
Aza TSAO-T derivatives bearing a substituted dihydroisothiazole dioxide ring with a phenyl group at 5'' position were prepared. Biological evaluation showed that phenyl group gives rise to a dramatical decrease of the inhibitory effect.
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