Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Adrenal androgen secretion and biologic effects.

A W Meikle1, R A Daynes, B A Araneo

  • 1University of Utah School of Medicine, Salt Lake City.

Endocrinology and Metabolism Clinics of North America
|June 1, 1991
PubMed
Summary

This review covers adrenal androgen secretion, exploring how factors like glucocorticoids, age, and stress influence it. Dehydroepiandrosterone exhibits unique effects, suggesting it acts as a steroid hormone itself.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measurement of thyroid stimulating immunoglobulins using a novel thyroid stimulating hormone receptor-guanine nucleotide-binding protein, (GNAS) fusion bioassay.

Clinical and experimental immunology·2012
Same author

Effects of testosterone replacement in human immunodeficiency virus-infected women with weight loss.

The Journal of clinical endocrinology and metabolism·2004
Same author

Androgen replacement in the treatment of Klinefelter's syndrome: efficacy and safety of a nonscrotal permeation-enhanced testosterone transdermal system.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2004
Same author

Transdermal testosterone gel: pharmacokinetics, efficacy of dosing and application site in hypogonadal men.

BJU international·2004
Same author

Pituitary radiographic abnormalities and clinical correlates of hypogonadism in elderly males presenting with erectile dysfunction.

The aging male : the official journal of the International Society for the Study of the Aging Male·2002
Same author

CpG DNA functions as an effective adjuvant for the induction of immune responses in aged mice.

Experimental gerontology·2001

Area of Science:

  • Endocrinology
  • Steroid hormone physiology

Background:

  • Adrenal androgens play crucial roles in various physiological processes.
  • Understanding the regulation of adrenal androgen secretion is vital for comprehending endocrine function.

Purpose of the Study:

  • To review the physiology of adrenal androgen secretion.
  • To discuss the impact of various factors on adrenal androgen levels.
  • To explore the direct biological effects of dehydroepiandrosterone.

Main Methods:

  • Literature review of studies on adrenal androgen secretion.
  • Analysis of factors influencing dehydroepiandrosterone levels.
  • Examination of dehydroepiandrosterone's non-metabolic biological activities.

Main Results:

Related Experiment Videos

  • Glucocorticoid administration, aging, stress, and certain drugs affect adrenal androgen secretion.
  • Dehydroepiandrosterone demonstrates significant biological effects, including on cytokine secretion, neoplasia, obesity, endothelial injury, and bone growth.
  • These effects are not fully explained by its metabolism into other steroid hormones.

Conclusions:

  • Dehydroepiandrosterone exerts direct steroid hormone actions.
  • Further research is warranted to fully elucidate the mechanisms of dehydroepiandrosterone's diverse biological effects.