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Related Experiment Video

Updated: Jul 6, 2026

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

Systemic hypertension and microalbuminuria.

Ana Maria Nunes de Faria Stamm¹, Gisele Meinerz, Jacqueline Consuelo da Silva

¹Hospital Universitário Prof. Dr. Polydoro Ernani São Thiago, Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil. stamm@ativanet.com.br

Arquivos Brasileiros De Cardiologia

|March 5, 2008

Summary

Microalbuminuria, a marker of kidney damage, affects 13.7% of treated hypertensive patients. It is significantly associated with target organ damage, especially cardiac lesions, in this population.

Related Experiment Videos

Last Updated: Jul 6, 2026

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

Area of Science:

Cardiology
Nephrology
Hypertension Management

Background:

Hypertension is a major risk factor for cardiovascular and kidney disease.
Microalbuminuria indicates early kidney damage and is a predictor of cardiovascular events.
Identifying target organ lesions in hypertensive patients is crucial for risk stratification.

Purpose of the Study:

To determine the prevalence of microalbuminuria and target organ lesions in treated hypertensive patients.
To investigate the association between microalbuminuria and target organ lesions in this population.

Main Methods:

An observational, descriptive, cross-sectional study was conducted.
153 hypertensive patients undergoing treatment were recruited from Internal Medicine and Cardiology Outpatient Clinics.
Data were collected between April and August 2006.

Main Results:

The prevalence of microalbuminuria was 13.7% (21/153).
The prevalence of target organ lesions was 48.4%, with cardiac lesions being the most common.
Target organ lesions were significantly more prevalent in patients with microalbuminuria (76.2%) compared to those without (43.9%) (p=0.006).

Conclusions:

A significant association exists between microalbuminuria and target organ lesions in treated hypertensive patients.
Microalbuminuria is particularly associated with cardiac lesions, even in the geriatric population.
These findings highlight the importance of screening for microalbuminuria in hypertensive patients to identify those at higher risk for target organ damage.