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Updated: Jul 6, 2026

Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition
Published on: February 8, 2018
Covert inhibition potentiates online control in a double-step task
1National Brain Research Centre, Near NSG Campus, Nainwal More, Haryana, India.
Inhibition, or withholding a planned action, was found to be faster when participants switched goals. This suggests that a baseline level of inhibition enhances online inhibitory control during complex tasks.
Area of Science:
- Cognitive Neuroscience
- Oculomotor Control
- Motor Inhibition
Background:
- Planned actions often require withholding responses.
- Online decision-making involves adjusting planned actions based on new information.
- The interaction between pre-planned inhibition and online adjustments is not fully understood.
Purpose of the Study:
- To investigate how pre-planned inhibition interacts with online decision-making in oculomotor control.
- To determine if withholding a planned saccade affects the ability to redirect gaze when new goals are introduced.
Main Methods:
- Subjects performed visually-guided (SV), memory-guided (MG), and delayed visually-guided (DV) saccades.
- A secondary target (target-step) was introduced in some trials, requiring saccade cancellation or redirection.
- Saccade inhibition time was calculated using a race model.
Main Results:
- Inhibition time was significantly shorter in memory-guided redirect (MGR) and delayed visually-guided redirect (DVR) tasks compared to standard visually-guided redirect (SVR) tasks.
- MGR (94 ms) and DVR (96 ms) showed faster inhibition than SVR (117 ms).
- This indicates facilitated online inhibition in MGR and DVR tasks.
Conclusions:
- A tonic level of inhibition interacts with online decision processes.
- This interaction potentiates inhibitory control during double-step tasks.
- Pre-existing inhibition may prime the system for faster response adjustments.
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