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KID syndrome

Ali Abdollahi1, Zahra Hallaji, Nafiseh Esmaili

  • 1Department of Ophthalmology, Farabi Hospital, Tehran University of Medical Sciences.

Dermatology Online Journal
|March 6, 2008
PubMed

Insights

Keratitis, Ichthyosis, and Deafness (KID) syndrome management improved with topical treatments. Simple emollients and keratolytics effectively treated skin hyperkeratosis, avoiding systemic retinoid risks.

Area of Science:

  • Dermatology
  • Genetics
  • Ophthalmology

Background:

  • KID syndrome is a rare congenital disorder.
  • It is characterized by keratitis, ichthyosis, and deafness.
  • Current management often involves addressing each symptom separately.

Observation:

  • A 4-year-old girl with KID syndrome was treated.
  • Treatment included bland emollients and topical keratolytics (urea).
  • Significant improvement in skin hyperkeratosis and palmoplantar keratoderma was observed.

Findings:

  • Topical therapies, specifically emollients and keratolytics, demonstrated efficacy.
  • These treatments improved skin manifestations of KID syndrome.
  • This approach offers an alternative to systemic retinoid therapy.

Implications:

  • Simple topical treatments may be a viable option for managing skin issues in KID syndrome.
  • This approach could potentially mitigate risks associated with systemic retinoid use.
  • Further research into topical therapy for KID syndrome is warranted.

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