Related Experiment Video
Updated: Jul 6, 2026
08:49
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Oral melanoma: an unusual presentation
Nara Lidia Lessa1, Andrea Braga Moleri, Flavio Merly
1Universidade do Grande Rio, Brasil.
Dermatology Online Journal
|March 6, 2008
Summary
Oral melanoma is a rare cancer often found late, leading to a poor five-year survival rate. This case highlights the challenges in diagnosing and treating this aggressive oral malignancy.
Area of Science:
- Oncology
- Oral Pathology
Background:
- Melanoma of the oral cavity is a rare malignancy.
- It accounts for 0.2% to 8% of all melanoma cases.
- Often diagnosed at advanced stages, contributing to a poor prognosis.
Observation:
- This clinical case presents a complex scenario.
- It involves intricate clinical and histopathological manifestations.
- Highlights the diagnostic and therapeutic challenges.
Findings:
- Oral melanoma is associated with a poor prognosis.
- Average survival time is approximately five years.
- Delayed diagnosis significantly impacts patient outcomes.
Implications:
- Emphasizes the need for early detection strategies for oral melanoma.
- Underscores the importance of thorough clinical and histopathological evaluation.
- Suggests a need for improved treatment protocols for advanced oral cancers.
Related Concept Videos
01:30Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
01:19Pigmentation
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
01:14Changes in Skin Color: Clinical Perspectives
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...