[Iatrogenic diseases in children based on the data from pathologicoanatomic autopsies]

Related Experiment Video

Updated: Aug 6, 2026

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma (DIPG)
08:46

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma (DIPG)

Published on: March 7, 2017

E D Cherstvoĭ, Iu E Nikiforov

    Arkhiv Patologii
    |January 1, 1991
    PubMed

    Insights

    Iatrogenic diseases, or illnesses caused by medical treatment, affected 37% of children in a 1988-1989 autopsy study. Complications from intensive care were the most common type, significantly impacting child mortality.

    Area of Science:

    • Pediatric Pathology
    • Medical Complications
    • Public Health

    Background:

    • Investigating iatrogenic diseases in pediatric populations is crucial for improving patient safety.
    • Understanding the incidence and types of iatrogenic harm in children is essential for medical practice.
    • This study examines autopsy data to quantify iatrogenic disease prevalence in deceased children.

    Observation:

    • A retrospective autopsy study of 500 children (1988-1989) identified iatrogenic diseases in 37% of cases.
    • The highest incidence of iatrogenic diseases was observed in neonates aged 7–28 days (65.8%).
    • Complications from resuscitation and intensive therapy constituted the majority (71.5%) of iatrogenic events, followed by surgical complications (19.2%).

    Findings:

    • Iatrogenic diseases were implicated as a cause or contributing factor in the death of 13.6% of the studied children.
    • The total number of identified iatrogenic diseases (270) surpassed the number of cases, indicating multiple instances per child.
    • Age-specific analysis revealed a higher vulnerability to iatrogenic harm in the post-neonatal period (7-28 days).

    Implications:

    • Findings highlight the significant burden of iatrogenic diseases in pediatric mortality, necessitating targeted prevention strategies.
    • The prevalence of intensive care-related complications underscores the need for enhanced safety protocols in neonatal and pediatric critical care.
    • This research provides critical data for medical education and policy development aimed at reducing iatrogenic harm in children.

    More Related Videos

    A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)07:01

    A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

    Published on: February 7, 2025

    Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review05:06

    Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review

    Published on: March 27, 2026

    Related Concept Videos

    Appendicitis-I: Introduction01:22

    Appendicitis-I: Introduction

    The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
    Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
    Acute Kidney Injury II: Pathophysiology01:29

    Acute Kidney Injury II: Pathophysiology

    Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
    Diphtheria01:28

    Diphtheria

    Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
    Introduction to Language of Pathophysiology l01:25

    Introduction to Language of Pathophysiology l

    Pathophysiology investigates how biological mechanisms—typically starting at the cellular level—disrupt normal bodily functions. It bridges anatomy and physiology to explain the progression of disease. With this foundation, it is important to understand the following key terms used to describe disease processes: Diagnosis:The process of identifying a disease using clinical evaluation, including signs (objective evidence like rashes), symptoms (subjective experiences like pain), laboratory test...
    Encephalitis l: Introduction01:19

    Encephalitis l: Introduction

    Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...