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Updated: Jul 6, 2026

Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles
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Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles

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Nanofluidic devices and their applications.

Patrick Abgrall1, Nam Trung Nguyen

  • 1Singapore-MIT Alliance/School of Mechanical and Aerospace Engineering, Nanyang Technological University, Nanyang Avenue, Singapore. abgrall@ntu.edu.sg

Analytical Chemistry
|March 7, 2008
PubMed
Summary
This summary is machine-generated.

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Fabricating nanochannel devices enables new insights into nanoscale fluid flow and biomolecule sieving. These nanofluidic systems offer advanced applications beyond traditional porous media.

Area of Science:

  • Nanotechnology
  • Fluid Dynamics
  • Biophysics

Background:

  • Micro- and nanotechnologies enable fabrication of deterministic nanochannel networks (1-100 nm).
  • Nanochannel dimensions are comparable to Debye length, biomolecule size, and slip length, imparting unique properties.
  • These devices offer superior control over geometry compared to traditional porous media.

Purpose of the Study:

  • To provide an overview of nanofluidic device fabrication technologies.
  • To discuss transport phenomena and applications of nanofluidic devices.
  • To highlight future challenges and potential applications in nanofluidics.

Main Methods:

  • Review of current nanofluidic fabrication techniques.
  • Analysis of fluid flow and biomolecule transport phenomena in nanochannels.

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Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles
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Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles

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Last Updated: Jul 6, 2026

Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles
11:13

Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles

Published on: March 13, 2016

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies
12:55

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies

Published on: November 27, 2013

Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles
10:14

Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles

Published on: March 6, 2016

  • Discussion of existing and emerging applications of nanofluidic devices.

    • Main Results:

    • Nanofluidic devices offer unique features due to controlled geometry and nanoscale dimensions.
    • These devices provide new insights into biomolecule sieving and nanoscale fluid dynamics.
    • Anisotropy enables novel separation principles in nanofluidic systems.

    Conclusions:

    • Nanofluidic devices represent a significant advancement over traditional porous media.
    • Further research into fabrication and transport phenomena will unlock new applications.
    • Future developments promise enhanced biomolecule separation and nanoscale fluid manipulation.