Related Experiment Video
Updated: Jul 6, 2026

Multi-Gene Single Nucleotide Polymorphism Detection in Gastric Cancer Based on Ion Semiconductor Sequencing Platform
Published on: May 10, 2024
Emerging drugs in the treatment of advanced gastric cancer
Eric D Tetzlaff1, Putao Cen, Jaffer A Ajani
1University of Texas, M.D. Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Houston, Texas 77030, USA.
Background:
Gastroesopheal cancer is one of the most common cancers worldwide. If detected early, curative treatment is possible. Often, gastroesophageal cancer is detected at an advanced stage when therapy is palliative.
Objectives:
To provide a critical evaluation of historic and recently developed chemotherapy regimens for the treatment of advanced gastroesophageal cancer (AGC).
Methods:
Published clinical trials in AGC as well as selected abstracts presented at international oncology meetings were selected.
Results/Conclusion:
Chemotherapy has demonstrated a benefit over best supportive care alone by improving the quality and quantity of life for patients with advanced disease. Recent Phase III trials investigating cytotoxic chemotherapy and Phase II trials incorporating biotherapy for the treatment of AGC show promise for the future.
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