Related Experiment Video

Updated: Jul 6, 2026

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
06:18

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

[Chikungunya in paediatrics: epidemic of 2005-2006 in Saint-Denis, Reunion Island]

S Ernould1, H Walters, J-L Alessandri

  • 1Service de pédiatrie, centre hospitalier départemental de Bellepierre, 97400 Saint-Denis, Réunion. antotiana@club-internet.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|March 7, 2008
PubMed

Insights

Chikungunya in children can present with severe neurological and cardiac complications, including fatal outcomes. Early recognition and treatment are crucial for pediatric Chikungunya cases, especially in infants under six months.

Area of Science:

  • Epidemiology
  • Pediatric Infectious Diseases
  • Clinical Medicine

Context:

  • Reunion Island experienced a significant Chikungunya (Chik) epidemic during the 2005-2006 summer.
  • Over one-third of the island's population was affected by the Chikungunya outbreak.

Purpose:

  • To describe the clinical characteristics and outcomes of pediatric Chikungunya cases.
  • To identify severe presentations and novel phenotypes in children affected by Chikungunya.

Summary:

  • A retrospective study analyzed 86 confirmed pediatric Chikungunya cases from January to April 2006.
  • Severe cases, particularly in infants under six months, involved neurological, cardiac, and gastro-intestinal complications.
  • Two fatal cases were reported, one due to central nervous system insult and another with multisystemic involvement. Three cases of epidermolysis bullosa were also identified.

Impact:

  • Highlights the potential for severe and fatal outcomes in pediatric Chikungunya.
  • Identifies specific risk factors and vulnerable populations (infants <6 months) for severe disease.
  • Underscores the need for further research into early and effective treatments for pediatric Chikungunya to prevent complications.
Abstract

More Related Videos

Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus10:35

Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus

Published on: May 31, 2020

Related Concept Videos

Yellow Fever01:18

Yellow Fever

Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...