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Related Concept Videos

The DNA Helix01:16

The DNA Helix

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The DNA Helix01:07

The DNA Helix

Deoxyribonucleic acid, or DNA, is the genetic material responsible for passing traits from generation to generation in all organisms and most viruses. DNA is composed of two strands of nucleotides that wind around each other to form a spring-like structure called a double helix. However, the double helix is not perfectly symmetrical. Instead, there are regularly occurring grooves in the structure. The major groove occurs where the sugar-phosphate backbones are relatively far apart. This space...
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DNA unwinding helicase enzymes are a type of motor protein. Motor proteins can translocate along filaments or polymers using energy generated from ATP hydrolysis. Helicases are involved in all the important cellular processes where DNA unwinding is required, such as DNA replication, repair, recombination, and transcription. They are present in all living organisms, but vary in their structure, function, and mechanism of action. For example, in prokaryotes, DnaB helicase binds and translocates...
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An organism’s genome needs to be duplicated in an efficient and error-free manner for its growth and survival. The replication fork is a Y-shaped active region where two strands of DNA are separated and replicated continuously. The coupling of DNA unzipping and complementary strand synthesis is a characteristic feature of a replication fork.   Organisms with small circular DNA, such as E. coli, often have a single origin of replication; therefore, they have only two replication forks, one in...
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An organism’s genome needs to be duplicated in an efficient and error-free manner for its growth and survival. The replication fork is a Y-shaped active region where two strands of DNA are separated and replicated continuously. The coupling of DNA unzipping and complementary strand synthesis is a characteristic feature of a replication fork.   Organisms with small circular DNA, such as E. coli, often have a single origin of replication; therefore, they have only two replication forks, one in...

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Updated: Jul 6, 2026

Scalable Nanohelices for Predictive Studies and Enhanced 3D Visualization
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Published on: November 12, 2014

And the helix may set you free.

Adam Coovadia1

  • 1Department of Pathology, All Children's Hospital, St. Petersburg, FL.

Journal of the Association of Genetic Technologists
|March 7, 2008
PubMed
Summary

DNA forensics, or genetic profiling, has evolved since 1983 to identify individuals and exonerate the wrongly convicted. Access to forensic evidence is crucial for exoneration, highlighting flaws in current legal frameworks.

Area of Science:

  • Forensic Science
  • Genetics
  • Law

Background:

  • DNA forensics, including DNA fingerprinting and genetic profiling, originated in 1983.
  • This technology has since become vital for individual identification and exonerating convicts.

Purpose of the Study:

  • To examine the role of DNA forensics in wrongful convictions and exonerations.
  • To highlight legislative barriers to accessing forensic evidence for exoneration.

Main Methods:

  • Review of historical application of DNA forensics.
  • Analysis of the impact of faulty forensic evidence on wrongful convictions.
  • Examination of legislative access to forensic evidence for exoneration.

Main Results:

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  • Faulty forensic evidence is a significant factor in wrongful convictions.
  • Limited access to forensic evidence impedes exoneration efforts.
  • DNA exonerations are prompting legislative reform in the U.S.
  • Conclusions:

    • DNA forensics is a powerful tool for justice, but its effectiveness is hampered by issues of access and accuracy.
    • Legislative reform is needed to ensure fair access to forensic evidence for all individuals, particularly those seeking exoneration.