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Related Concept Videos

Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Acute Pancreatitis II: Pathophysiology01:21

Acute Pancreatitis II: Pathophysiology

The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Ascites01:19

Ascites

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Related Experiment Video

Updated: Jul 6, 2026

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
20:33

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing

Published on: July 4, 2019

Abdominal compartment syndrome: effects on organ function.

M Stamatakos1, S Tsaknaki, R Iannescu

  • 12nd Department of Propaedeutic Surgery, University of Athens, School of Medicine, Laiko General Hospital, Athens, Greece. stamatakosmih@yahoo.gr

Chirurgia (Bucharest, Romania : 1990)
|March 8, 2008
PubMed
Summary
This summary is machine-generated.

Abdominal compartment syndrome (ACS) is a critical condition causing organ issues and is increasingly studied in intensive care. Understanding ACS can improve management and reduce multiple organ failure (MOF) and mortality.

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Controlled Reversible Visceral Arterial Ischemia, Venous Congestion and Combined Malperfusion via Midline Laparotomy in Rats
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Controlled Reversible Visceral Arterial Ischemia, Venous Congestion and Combined Malperfusion via Midline Laparotomy in Rats

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Last Updated: Jul 6, 2026

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
20:33

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Published on: July 4, 2019

Controlled Reversible Visceral Arterial Ischemia, Venous Congestion and Combined Malperfusion via Midline Laparotomy in Rats
04:57

Controlled Reversible Visceral Arterial Ischemia, Venous Congestion and Combined Malperfusion via Midline Laparotomy in Rats

Published on: July 5, 2024

Area of Science:

  • Critical care medicine
  • Surgical pathology

Background:

  • Abdominal compartment syndrome (ACS) is a significant clinical issue with increasing incidence.
  • ACS is a known cause of various abdominal and extra-abdominal pathologies.
  • It is a critical condition that can lead to multiple organ failure (MOF).

Purpose of the Study:

  • To highlight the rising importance of ACS in intensive medical care.
  • To emphasize the potential of improved understanding of ACS for better patient outcomes.
  • To explore how managing ACS can limit MOF and mortality.

Main Methods:

  • Literature review on ACS incidence and impact.
  • Analysis of ACS as a precursor to MOF.
  • Discussion of current intensive care management strategies for ACS.

Main Results:

  • ACS is a growing concern in intensive care settings.
  • ACS is linked to a wide range of pathologies.
  • Effective management of ACS is crucial for preventing MOF.

Conclusions:

  • Further research into ACS is warranted.
  • Better understanding of ACS can lead to improved patient survival rates.
  • Timely intervention in ACS may reduce the incidence of MOF and associated mortality.