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Updated: Jul 6, 2026
03:23
Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
[Drug-induced eosinophilic pneumonia].
J Schelhorn1, L Höfer, G Syrbe
1Klinik für Neurologie, Asklepios Fachklinikum, Bahnhofstrasse 1A, Stadtroda, Germany. J.Schelhorn@asklepios.com
Der Nervenarzt
|March 8, 2008
Summary
Nitrofurantoin can cause eosinophilic pneumonia, a lung disorder. This drug-induced lung condition is often hard to diagnose, especially in patients with chronic neurological conditions like multiple sclerosis.
Area of Science:
- Pulmonology
- Pharmacology
- Neurology
Background:
- Eosinophilic pneumonia is a lung disorder defined by eosinophilic infiltration of the lungs and elevated blood eosinophil counts.
- Drug-induced lung injury is a significant cause of eosinophilic pneumonia, often presenting subtly.
- Diagnosing mild forms or cases in neurologically impaired patients can be challenging.
Observation:
- A 46-year-old woman with a history of multiple sclerosis presented with symptoms suggestive of a lung disorder.
- The patient had been prescribed nitrofurantoin, a common antibiotic used for urinary tract infections.
Findings:
- The patient was diagnosed with eosinophilic pneumonia.
- The pneumonia was attributed to nitrofurantoin, indicating a drug-induced etiology.
- The case highlights the potential for nitrofurantoin to cause pulmonary eosinophilia.
Implications:
- This case underscores the importance of considering drug-induced lung diseases, particularly nitrofurantoin-induced eosinophilic pneumonia, in patients with neurological conditions.
- Early recognition and discontinuation of the offending drug are crucial for favorable outcomes.
- Further research may elucidate the specific mechanisms and risk factors for nitrofurantoin-induced pulmonary complications.
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