Rhabdoid and papillary meningioma with leptomeningeal dissemination

Area of Science:

• Neuro-oncology
• Pathology of the Central Nervous System

Background:

• Rhabdoid meningioma is a rare, aggressive variant of meningioma, classified as WHO Grade III.
• Dissemination into cerebrospinal fluid (CSF) is an exceptionally uncommon presentation for this tumor type.

Observation:

• A young male patient with a history of two prior surgeries presented with multiple instances of CSF seeding throughout the brain and spinal cord.
• Advanced imaging techniques, including diffusion and perfusion MRI sequences, were utilized to characterize the tumor and its spread.

Findings:

• The case demonstrates extensive leptomeningeal metastasis of rhabdoid meningioma, a finding rarely documented.
• Imaging findings correlated with the aggressive nature and dissemination potential of this specific meningioma subtype.

Implications:

• This case underscores the critical need for aggressive management strategies for rhabdoid meningiomas due to their poor prognosis.
• Highlighting rare presentations like CSF seeding is crucial for improving diagnostic accuracy and treatment planning in neuro-oncology.