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Related Experiment Video

Updated: Jul 6, 2026

The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice
07:09

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Published on: July 16, 2014

[Chronic sciatic pain caused by sciatic nerve schwannoma].

C Blanchard1, P Dam-Hieu, F Zagnoli

  • 1Service de neurologie, hôpital d'instruction des armées Clermont-Tonnerre, rue du Colonel-Fontferrier, 29240 Brest Naval, France. christian.blanchard@dbmail.com

La Revue De Medecine Interne
|March 8, 2008
PubMed
Summary
This summary is machine-generated.

Schwannomas can cause chronic sciatica, mimicking herniated disc pain. Early diagnosis and surgical removal of sciatic nerve schwannomas can provide complete pain relief.

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Area of Science:

  • Neuro-oncology
  • Orthopedic Surgery
  • Pain Management

Background:

  • Schwannomas are nerve sheath tumors that can present with slowly progressive, often painful, symptoms.
  • Sciatic nerve schwannomas can mimic symptoms of lumbar disc herniation, leading to diagnostic challenges.
  • Clinical and radiological examination of the sciatic nerve is crucial when lumbar pathology is ruled out.

Observation:

  • A patient presented with chronic sciatica without lumbar pain and a normal lumbar MRI.
  • Physical examination revealed a painful mass with a Tinel sign in the patient's back thigh.
  • Magnetic Resonance Imaging (MRI) identified a multilobular mass along the sciatic nerve.

Findings:

  • The patient was diagnosed with a plexiform schwannoma involving the sciatic nerve.
  • Surgical excision of the schwannoma was performed.
  • Post-operative follow-up indicated complete relief from sciatic pain.

Implications:

  • This case highlights the importance of considering sciatic nerve schwannomas in the differential diagnosis of chronic sciatica.
  • Early and accurate diagnosis through clinical and radiological assessment is key for effective management.
  • Surgical intervention for sciatic nerve schwannomas can lead to successful pain resolution.