[Pathomorphological features of pulmonary tuberculosis at different stages of HIV infection: autopsy data]

The case histories, autopsy protocols, and histological specimens from 11 patients who had died from HIV-associated tuberculosis and 15 patients died from progressive disseminated tuberculosis and caseous pneumonia in the absence of HIV infection (a control group). In all the study patients, the morphology of the lung and peripheral and intrathoracic lymph nodes was examined at the early (2B) and late (4B-5) stages of HV infection (Groups 1 and 2, respectively). Group 1 patients had died from caseous pneumonia. Their morphology of tuberculosis differed little from that in the control group. Group 2 was marked by a predominance of disseminated tuberculosis with extensive exudative necrotic lesions in the lung, lymph nodes, and other organs in the presence of reduced lymphoid tissue and in the absence of a limited epitheloid cell reaction.