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Ketoconazole-induced fulminant hepatitis necessitating liver transplantation
T E Knight1, C Y Shikuma, J Knight
1Department of Medicine, John A. Burns School of Medicine, Honolulu, Hawaii.
Journal of the American Academy of Dermatology
|August 1, 1991
Abstract:
The most serious side effect of ketoconazole is hepatitis, which has proved fatal in seven reported cases. We present a case of fulminant hepatic failure in a 45-year-old Oriental woman that probably would have been fatal except for a successful liver transplant. A review of the literature of fatalities associated with ketoconazole is presented.