Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Encephalitis and catatonia treated with ECT.

Sherese Ali1, Charles A Welch, Lawrence T Park

  • 1Department of Neuropsychiatry, Toronto Western Hospital, Toronto, Ontario, Canada. sherese.ali@uhn.on.ca

Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology
|March 11, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fit-for-purpose application of LC-MS in protein bioanalysis, case studies shared within the European Bioanalysis Forum Hybrid MS team.

Bioanalysis·2026
Same author

Interim Effectiveness of 2025-2026 mRNA-1283 and BNT162b2 COVID-19 Vaccines Against COVID-19-Related Outcomes Among Adults Aged ≥ 65 Years in the United States.

Infectious diseases and therapy·2026
Same author

Comparative Effectiveness of mRNA-1273 Versus Protein-Based NVX-CoV2705 Vaccination on COVID-19-Related Outcomes Among Insured Adults in the United States During 2024-2025: A Retrospective Matched Cohort Study.

Advances in therapy·2026
Same author

Incidence of COVID-19 and Influenza-Related Outcomes and Vaccinations in the United States, October 2022 Through December 2024.

Vaccines·2026
Same author

Translation, cultural adaptation, and validation of the amharic version of the Minnesota Living with Heart Failure Questionnaire (MLHFQ).

Journal of patient-reported outcomes·2026
Same author

"It's a big, round circle of knowledge to me. I don't know how else to explain it": strengthening cultural identity through Indigenous placekeeping and food sovereignty practices in Kingston, Ontario.

AlterNative (Auckland, N.Z. : 2005)·2026
Same journal

A World Appears: A Journey into Consciousness: Pollan M. 2026. New York: Penguin Press. 280 pages. List price: $23.09.

Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology·2026
Same journal

Parallel Distributed Processing and Other Computational Models: Strengths, Weaknesses, and Possibilities.

Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology·2026
Same journal

Serum SIRT3 Levels and Their Relationship With Alzheimer Disease Pathological Markers in Individuals With Mild Cognitive Impairment.

Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology·2026
Same journal

Not Just for Adults: Transient Global Amnesia is Rare-But Possible-in Children.

Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology·2026
Same journal

Mysteries of the Social Brain: Understanding Human Behavior Through Science: Miller BL, Sturm V. New York: Routledge. 2024. 146 pages. List price $28.99.

Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology·2026
Same journal

Emotion Perception in Behavioral Variant Frontotemporal Dementia and Alzheimer Disease: The Parahippocampal Conundrum.

Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology·2026
See all related articles

Malignant catatonia can arise from encephalitis, potentially worsening with neuroleptic medication. Electroconvulsive therapy (ECT) proved effective in treating this severe condition in two encephalitis patients.

Area of Science:

  • Neurology
  • Psychiatry

Background:

  • Neuropsychiatric symptoms, including catatonia, can indicate limbic encephalitis or encephalitides of unknown cause, such as encephalitis lethargica.
  • Catatonia in encephalitis is challenging to diagnose, often leading to neuroleptic use, which can exacerbate the condition.

Observation:

  • Two cases of encephalitis presented with neuropsychiatric symptoms, including catatonia.
  • Patients received neuroleptic treatment for agitation, which complicated their catatonic state, leading to malignant catatonia.

Findings:

  • Both patients experienced significant improvement following electroconvulsive therapy (ECT).
  • Lorazepam, while helpful for catatonia, was insufficient in these severe cases.

Implications:

Related Experiment Videos

  • Malignant catatonia is a serious complication of encephalitis lethargica and idiopathic limbic encephalitis, increasing mortality risk.
  • Physicians should exercise caution with neuroleptics in encephalitis patients due to the risk of precipitating malignant catatonia.
  • Early consideration of ECT is crucial for malignant catatonia, especially when secondary to encephalitis and unresponsive to lorazepam.